The Computer Science and Engineering department was well represented at ASPLOS 2016, the 21st ACM International Conference on Architectural Support for Programming Languages and Operating Systems. It took place April 2-6 at Georgia Tech in Atlanta. CSE Prof. Yuanyuan (YY) Zhou is chairing the conference this year. She also chaired the Program Committee, which included fellow CSE Prof. Michael Taylor. Zhou calls ASPLOS “the premier forum for multidisciplinary systems research spanning computer architecture and hardware, programming languages and compilers, operating systems and networking, as well as applications and user interfaces.” Zhou notes that sessions dealt with performance, energy and thermal efficiency, as well as resiliency, security and sustainability, as computer scientists grapple with the explosion of big data, increasing human-centered applications, and widely varying scales from ultra-low-power wearable devices to exascale parallel and cloud computing. The program included two keynotes, a debate, and 53 papers.